Add the ground beef to a pan. Break into bite-size pieces and season with 1/4 teaspoon garlic powder, 1/4 teaspoon onion powder, salt, and pepper. Drain any grease.
In a small bowl, whisk together the light mayonnaise, dill relish, ketchup, mustard, vinegar, 1/4 teaspoon garlic powder, and 1/4 teaspoon onion powder.
Lay out a tortilla and top it with 1/2 slice of cheese, 1/2 cup of ground beef, lettuce, onion, pickles, 1 1/2 tablespoons of the Big Mac sauce, then roll it up.